Postpartum Depression: Is Brexanolone the Answer?

Postpartum Depression: Is Brexanolone the Answer?



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hi oh I wanted to hop on here in response to a post that I put up yesterday about Breck's an alone which is the latest fda-approved drug for postpartum depression and just in case you think postpartum depression doesn't affect you or you're not a woman or a mother the way that we regard our mothers in society is in my opinion a great barometer for our level of disconnection disconnection from nature disconnection from culture disconnection from the community from each other and even from this concept which is stripped from every aspect of conventional medicine of the soul disconnection from the soul and I have been working in my own sort of spiritual quest to move beyond this idea that we are here to fight the pharmaceutical industry and all of the evils that they pervade and instead to simply raise awareness of patterns so that when we know better we can do better because the truth is that a medication like this one which I'll tell you a bit about is itself a symptom of a great degree of distress and misalignment in this culture and society and of course the American perspective on health is becoming the dominant orthodoxy the world over crushing more indigenous perspectives on how relate to struggle and suffering so our symptoms as a collective here in America include that we feel it is appropriate and potentially even necessary to subdue women who are struggling in their most vulnerable moment and it's my perspective and the perspective of others that there are times in a woman's hormonal and cyclical life where the veil is thin and where what was a little tap on her shoulder you know pay attention to this pay attention to this becomes a very very loud and difficult to ignore banging on the door and that can happen during the premenstrual window and it certainly can happen postpartum it can also happen perimenopausal II and the women who are perhaps most sensitive to misalignment these Canaries in the coal mine are the ones who are going to manifest these symptoms of distress most significantly and severely now what is misalignment right so so the imperative here is to ask what is going on why is this happening and not to assume that we have a disease model that is verified through some understood biochemical mechanism or structure or pathology right that doesn't exist that's a myth so in fact we have to ask each individual woman what is going on for you why is expressing itself in this way and you know as far as I've ever explored with the women I've worked with there are many many many different answers to that why and they're highly personal highly personal to their journey and their story to their particular patterns their particular wounds and you know they can also be relatively mundane you know there are physiological balances whether it's micronutrient deficiencies because of a long-standing deficient diet or there can be inflammatory processes representing themselves as autoimmune conditions like Hashimoto's or postpartum thyroiditis there can be toxic exposures that accumulate and manifest in cognitive behavioral or mood related symptoms and simultaneous to that narrative to that physiologic narrative are other psychological emotional and spiritual layers and one that I feel most passionately about is that we are not as women designed nor should we be to raise children in isolation the way that we are and no mommy groups and breastfeeding circles do not count as a great mitigator to the unraveling of our tribe the unraveling of community children have since ancestral history been raised by the collective by many many many eyes that they wake up to that know them that see them that reflect to them a deep sense of care and holding and now in our modular family homes women are spending massive amounts of time struggling alone in in the care of their infants without the wisdom of their sisters aunts mothers grandmothers to help support their intuition that's been papered over and buried by masculinized orientation towards life productivity achievement and work performance right we need to remember again how to be women how to be mothers and we don't have that support and instead we're doing this by ourselves and and I think that if you reflect on human history it makes a good amount of sense that it would be a great alarm signal right for a woman to ever be left alone with a baby when in history when in tribal history would a woman ever ever ever be alone with a baby wouldn't that be a grave and significant you know signal of danger wouldn't her nervous system want to poise itself to respond to whatever horrific thing had happened to the rest of her tribe to leave her alone with this infant right so whether you're looking at this from a socio-cultural perspective or a basic physiologic perspective around hormonal shifts and inflammatory processes and you know gut brain access dysfunction however you're looking at it how could it be in the best interest of a woman who is struggling in this vulnerable moment to sedate her how and I really don't want to hear that there's such a thing as an urgent emergency that warrants this kind of intervention and it's life-saving right because that's often the what I refer to as the Stockholm Syndrome that women who defend the pharmaceutical industry's posture on these things offer is how could you take this away from women who need it right and I think that the only way that we would defend our access to drugs because let's call them what they are right that are here and intended to subdue and sedate and really suppress deeply suppress our felt experience is if we ourselves have forgotten what it is that we're here for what we are entitled to and what we deserve and we can't afford that alone it's the rare woman who is strong enough to uphold that alone we need the collective to uphold this for us we need to shift the conversation around what women deserve in pregnancy and postpartum and what infants deserve when it comes to the protection of that dyad and so in service of that I think it's important to know what trained experts are now going to be recommending to women who are struggling with symptoms of you know sleep change mood change energy and motivation change may be suicidal thoughts may be thoughts of harm and there's actually quite an interesting perspective around why it is that women often experience thoughts of harming their baby thoughts of harming themselves intrusive thoughts as they're called and it has nothing to do with any intention to do so right and in fact if you know the media making case of women who have in fact gone on to harm their infants and babies you will find that in every single one of those instances those women were recently medicated with drugs that themselves induce altered states of consciousness that can lead to impulsive violence there is as far as I know not in media making exception to this right so if we appreciate that there may be a way to interact with this struggle that helps us to understand what is at the root of it then we might make different choices it's also important to know what there is to know about these drugs right and that's called informed consent so you might want to know that Brett's an alone which is an aloe pregnenolone analogue right it's a synthetic neuro steroid that is considered because really not much is known about it it's considered to be a in the class of the benzodiazepines and if you know anything or have been psychiatrically injured by you know by the standard of care and you've been treated with something like klonopin or ativan or valium or xanax then you know that this is a category potentially not to be taken lightly because it's not going to be your prescribing doctor who's going to be helping you to transition out of a medicated dependent state maybe five seven eight years ten years fifteen thirty years after having been started on a medication that was intended to just kind of take the edge off right so it's in this class it is incredibly a – our intravenous infusion and with this medication in the FDA briefing on it it is recommended that women are not the primary caretakers of their infants right so already we have an inbuilt separation not unlike the hospital hospital institutionalized separation of women and newborn at the moment of birth for purposes related to unnecessary interventions so we have institutionalized separation as a part of this medication based treatment we also don't have information and probably won't ever really have good quality information on what it is for an infant who is exposed through breast milk to this medication so odds are it's going to be recommended that breastfeeding be stopped for this treatment okay so so we're separating the mom from her child where potentially recommending potentially that she consider cessation of breastfeeding for what gain right so do we have evidence that this is a life-saving intervention well are you convinced by three three randomized placebo-controlled trials inclusive of 274 women that separated from placebo at sixty hours only by four points on what's called the Hamilton scale so whenever you're working with a sedative you're going to have an artifact of impact and effect right and four points on the Hamilton scale if you know anything about it it's not impressive it's not even really according to many clinically significant and what's fascinating is in the FDA briefing itself this distinction you know this this separation from policy itself disappears at 30 days right where placebo actually has a more measured impact than the drug itself so the SIBO comes up in efficacy and the drug sort of stays the same and that is the basis ladies and gentlemen for this most recent recommendation and if you don't know the back story and you don't consider the cultural context of what it is to support a medication intervention like this then you might think well why not right women need help and if anyone can relate to that it's me because I spent the better part of my conventional career as a psychiatrist medicating pregnant and breastfeeding women that was my specialty as one of the first 300 reproductive psychiatrists in the world and I did that because I believed that this was a way to help women I believe that suffering was bad and meaningless and that there was no reason to endure it and whatever we could do to mitigate symptoms was the right thing to do and I know that the doctors who will go on to recommend this medication are not bad people and they're not here to do harm and that's why the onus is on us the onus is on us as a collective as a community to begin a different kind of conversation about this so that a woman who is in this position will have a friend will have a loved one who can speak to her about the greater broader truth about what it might mean that she's going through this about what it might indicate that she needs whether it is a higher level of self-care whether it is a higher level of nutrition whether is additional meaningful support whether it's an investigation into an imbalance that could be easily corrected through lifestyle medicine whether it's an exploration of lineage level trauma that's coming through her from her ancestry we don't know she knows and she needs support and exploring that and as I often say those who are labeled as mentally ill and captured by a system that seeks to medicate them for life and to keep them dependent on a paradigm that sees them as fundamentally broken these are the beacons really the the visionaries for our future on this planet they are the most sensitive their body mind and spirit cannot tolerate the that is going on cannot tolerate the synthetic diet the toxic exposures the unraveling of our communities the you know meaningless commitment to survival level priorities around you know work and this this hollow grind that we subscribe to the nine-to-five punching the clock they cannot abide right so their souls are essentially saying no and if we medicate those people we will be lost forever for good and it may represent our demise and I know this because when I facilitate liberating these people from their medication histories from their labels from their perspective on themselves as being broken I see a light come from them that is blank so I hope that you know we can orient around I love the Christian birdie quote that it's it's no sign of health to be well adapted to a profoundly sick Society so can we acknowledge that there unlike psychiatry that there are things profoundly wrong and can we move towards people who are expressing symptoms of that misalignment with a greater amount of compassion and embrace of what it is that they're responding to with a sensitized level of support rather than a one-size-fits-all means of saying no to what they are experiencing to what is very real for them and especially when that one-size-fits-all means of saying no includes adverse effects like loss of consciousness and the the 60 hour endurance fest of a IV medication treatment so we can do better than this and I hope that this has helped to add some nuance to the conversation about the latest greatest offering from the pharmaceutical industry for the new mothers among us thanks for listening

9 thoughts on “Postpartum Depression: Is Brexanolone the Answer?

  1. Thank you Dr about your discussion of raising kids in a community. I am struggling and feel so alone and isolated as a fairly new mom. I wish I had that close knit community you speak of. It is so so important. I live far from my family and don’t have many friends close by.

  2. Why do you charge over $4,000 for an initial consult while simultaneously saying vaccines are just for the money?

    How can you claim vaccines haven't been tested, while advocating for coffee enemas?

    If you know so much more than every other doctor, why don't you work with sick people any more?

    How much money do you make from your online store, online course, and book?

    You claim to have done "research" in vaccines. Do you use an IRB?

    Will you ever answer the most popular question asked on you FB page?

  3. Can you speak about how other cultures support mothers in this process of raising children. I dont feel that value in this society. It's very isolating. If you look at Japan as well as other countries females are not producing children. Then, the country slowly dies.

  4. Thank you so much for this conversation. As a woman with a 7 month old who has been diagnosed with depression, it is VITALLY important to communicate to our Western medicine doctors that I am not broken. We are not broken. I told my doctor I was using a holistic treatment plan and she rolled her eyes. Thank you so much for your work. Blessings to you and infinite energy. đź’™

  5. Buenos tardes si podría poner sus vídeos en subtitulos para poder leer en Español y así poder recibir su importantísima información verdadera que transmite muchas gracias

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