BIOESSAYS: Fetal microchimerism and maternal health

BIOESSAYS: Fetal microchimerism and maternal health



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During pregnancy, fetal cells migrate into the maternal body and persist post-partum. This BioEssays review reports microchimerism is associated with maternal health and disease. Using an evolutionary framework, the authors of this review predict conditions in which fetal cells contribute to maternal health and those where they may manipulate maternal tissue, contributing to disease.

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this is a story about the mysteries of life where myth meets reality where science meets science fiction where two bodies collide and fact is stranger than fiction we all know where babies come from but do we know the power of what they leave behind their reach extends far beyond the womb as our protagonist dr. body is experimenting in the lab an unstoppable transformation is occurring within during pregnancy fetal cells are passing through the placenta and into her body integrating into dr. body's tissues and transforming her into super chimera fetal cells move right in and become the guests that will not leave until immediately following birth super chimera cells spring into action removing the intruders except that not all fetal cells are kicked out some fetal cells persist staying for decades after birth hiding proliferating and sometimes even transforming the body what are these cells really doing – super chimera well sometimes they aren't doing much sometimes they come to the rescue racing to the site of injury to help super Chimera heal but super chimeras strength is also her greatest weakness her body is rife with internal conflict sometimes fetal cells want more than she can give helpful harmful it may seem fetal cells are bit two-faced doctor body and other scientists are working to unmask the mysteries behind super chimeras power and vulnerabilities for the good of man and woman kind

4 thoughts on “BIOESSAYS: Fetal microchimerism and maternal health

  1. Nice animations! Overall, a great effort towards educating the public.
    It would have been informative to include that the transfer is bi-directional (mother to fetus as well as fetus to mother) and that there is microchimerism associated with blood transfusion after trauma. Also very useful to the public's understanding of microchimerism would be a discussion of the types of assays used and their detection limits – as in why studies of male microchimerism are so prevalent.

  2. Fantastic video brings to life a little known and mysterious phenomenon – fetal cell microchimerism. This is an excellent example of science communication.

  3. Stop anthropomorphizing biological functions, people. Fetal cells are not "intruders" in the baby's mother's body. It is a natural and beneficial process. During pregnancy, the baby's sloughed-off cells migrate to his/her mother's heart to repair damage. Boys' cells remain within their mothers' bodies, and evidence shows the cells help protect the mothers' brains from developing Alzheimer's disease later in life.

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